Publication list
De Benedetti S, Kirilov NK, Zeng H, Ade C, Bodenstein I, Förster M, Abdel-Wadood N, Aljohmani A, Krasteva-Christ G, Yildiz D, Junker S, Khalid SJ, Rox K, Schrey H, Grofle M, Schiefer A, Becker SL, Pfarr K, Hoerauf A, Bischoff M, Müsken M, Schneider T. Breaking down barriers: CorA effectively targets staphylococcal biofilms in vitro and in vivo. ChemMedChem 2026. doi: 10.1002/cmdc.202501057
Karačić J, Grosse M, Pfarr K, Schiefer A, Schneider T, Hoerauf A, Karačić S, Parčina M, Hischebeth G, Fröschen FS, Bierbaum G. Corallopyronin A exhibits potent activity against staphylococci including MRSA and isolates from prosthetic infections. Infection 2026. doi: 10.1007/s15010-026-02760-8.
Klümpen L, Mantri A, Philipps M, Seel W, Schlautmann L, Yaghmour MH, Wiemann V, Stoffel-Wagner B, Coenen M, Weinhold L, Hasenauer J, Fließwasser T, Burgdorf S, Thiele C, Stehle P, Simon M-C. Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial. Nat Commun. 2026. doi: 10.1038/s41467-026-68303-9
Kränkel L, Hauser J, Slavetinsky J, Zinser A, Schmidt A, Nega M, Elsherbini AMA, Schneider T, Gille C, Schaller M, Fuchs J, Peschel A, Slavetinsky C. Polygenic, cell-envelope adaptations drive high-frequency daptomycin resistance in Staphylococcus capitis NRCS-A from neonatal sepsis and NEC. Antimicrob Agents Chemother 2026. doi: 10.1128/aac.01414-25
Overman G, Loeckener I, Williford Z, Davis S, Diallo A, Blair J, Henrichfreise B, Liechti GW. Chlamydia trachomatis restricts signaling through NOD2 until late in the pathogen’s developmental cycle. Infect Immun 2026. doi: 10.1128/iai.00472-25
Torres-Puschel D, Zimmer L, Kehraus S, Abdelrahman AA , Schneider T, Müller A, Carlier A, Crusemann, M. Paenidepsins are a family of lipopeptides from paenibacillus. J Nat Prod 2026. doi: 10.1021/acs.jnatprod.5c01579
Deschner F, Mostert D, Daniel J-M, Voltz A, Schneider DC, Khangholi N, Bartel J, de Carvalho LP, Brauer M, Gorelik TE, Kleeberg C, Risch T, Haeckl FPJ, Herraiz Benítez L, Andreas A, Kany AM, Jézéquel G, Hofer W, Müsken M, Held J, Bischoff M, Seemann R, Brötz-Oesterhelt H, Schneider T, Sieber S, Müller R, Herrmann J. Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets. Cell Chem Bio 2025. doi: 10.1016/j.chembiol.2025.03.005
Rasheed S, Umstaetter F, Muehlberg E, Beijer B, Hertlein T, Klika KD, Kleist C, Werner J, Domhan C, Bingel M, Mueller A, Rausch M, Zimmermann S, Ohlsen K, Haberkorn U, Koch M, Bischoff M, Schneider T, Mueller R, Herrmann J, Mier W, Uhl P. Antibiotic-polycationic peptide conjugation as an effective strategy to overcome daptomycin resistance. Adv Therap 2025. doi: 10.1002/adtp.202400473
Sugrue I, Ade C, O'Connor PM, Daniel JM, Innocenti P, Kirsch N, Martin NI, Weindl G, Hill C, Schneider T, Paul Ross R. Trans-kingdom conservation of mechanism between bacterial actifensin and eukaryotic defensins. NPJ Antimicrob Resist 2025. doi: 10.1038/s44259-025-00135-x
Treiber T, Li WS , Bingel M, Müller A, Eckhardt M, Menche D. Total synthesis of epicoccolides A and B by oxidative skeleton rearrangement Leads to a structural revision and questions the proposed biosynthesis. Org Lett 2025. doi: 10.1021/acs.orglett.5c02032
Adeniyi ET, Kruppa M, De Benedetti S, Ludwig KC, Krisilia V, Wassenberg TR, Both M, Schneider T, Müller TJJ, Kalscheuer R . Synthesis of bisindole alkaloids and their mode of action against methicillin-resistant Staphylococcus aureus. ACS Infect Dis 2024. doi: 10.1021/acsinfecdis.3c00657
Buijs NP, Vlaming HC, Kotsogianni I, Arts M, Willemse J, Duan Y, Alexander FM, Cochrane SA, Schneider T, Martin NI. A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens. Proc Natl Acad Sci U S A 2024. doi: 10.1073/pnas.2315310121
Dreckmann TM, Fritz L, Kaiser CF, Bouhired SM, Wirtz DA, Rausch M, Müller A, Schneider T, König GM, Crüsemann M. Biosynthesis of the corallorazines, a widespread class of antibiotic cyclic lipodipeptides. RSC Chem Biol 2024. doi: 10.1039/d4cb00157e
Lewis K, Lee RE, Brötz-Oesterhelt H, Hiller S, Rodnina MV, Schneider T, Weingarth M, Wohlgemuth I. Sophisticated natural products as antibiotics. Nature 2024. doi: 10.1038/s41586-024-07530-w
Löckener I, Behrmann LV, Reuter J, Schiefer A, Klöckner A, Krannich S, Otten C, Mölleken K, Ichikawa S, Hoerauf A, Schneider T, Pfarr KM, Henrichfreise B. The MraY inhibitor muraymycin D2 and its derivatives induce enlarged cells in obligate intracellular Chlamydia and Wolbachia and break the persistence phenotype in Chlamydia. Antibiotics 2024. doi: 10.3390/antibiotics13050421
Ludwig KC, Puls J-S, Matos de Opitz CL, Innocenti P, Daniel J-M, Bornikoel J, Arts M, Krannich S, Straetener J, Brajtenbach D, Henrichfreise B, Sass P, Müller A, Martin NI, Brötz-Oesterhelt H, Kubitscheck U, Grein F, Schneider T. The dual mode of antibacterial action of the synthetic small molecule DCAP involves lipid II binding. JACS 2024. doi: 10.1021/jacs.4c05138
van Groesen E, Mons E, Kotsogianni I, Arts M, Tehrani KHME, Wade N, Lysenko V, Stel FM, Zwerus JT, De Benedetti S, Bakker A, Chakraborty P, van der Stelt M, Scheffers DJ, Gooskens J, Smits WK, Holden K, Gilmour PS, Willemse J, Hitchcock CA, van Hasselt JGC, Schneider T, Martin NI. Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Sci Transl Med 2024. doi: 10.1126/scitranslmed.abo4736
Puls J-S, Winnerling B, Power JJ, Krüger AM, Brajtenbach D, Johnson M, Bilici K, Camus L, Fließwasser T, Schneider T, Sahl H-G, Ghosal D, Kubitschek U, Heilbronner S, Grein F. Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action. ISME J 2024. doi: 10.1093/ismejo/wrae044
Voitsekhovskaia I, Ho YTC, Klatt C, Müller A, Machell DL, Tan YJ, Triesman M, Bingel M, Schittenhelm RB, Tailhades J, Kulik A, Maier ME, Otting G, Wohlleben W, Schneider T, Cryle M, Stegmann E. Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues. Proc Natl Acad Sci U S A 2024. doi: 10.1039/d4cb00140k
Adolf LA, Müller-Jochim A, Kricks L, Puls JS, Lopez D, Grein F, Heilbronner S. Functional membrane microdomains and the hydroxamate siderophore transporter ATPase FhuC govern Isd-dependent heme acquisition in Staphylococcus aureus. Elife 2023. doi:10.7554/eLife.85304.
Brajtenbach D, Puls JS, Matos de Opitz CL, Sass P, Kubitscheck U, Grein F. Quantitative analysis of microscopy data to evaluate bacterial responses to antibiotic treatment. Methods Mol Biol 2023. doi: 10.1007/978-1-0716-2855-3_12
Deisinger JP, Arts M, Kotsogianni I, Puls JS, Grein F, Ortiz-Lopez FJ, Martin NI, Müller A, Genilloud O, Schneider T. Dual targeting of the class V lanthipeptide antibiotic cacaoidin. iScience 2023. doi: 10.1016/j.isci.2023.106394
Kümpel C, Grein F, Dahl C. Fluorescence microscopy study of the intracellular sulfur globule protein SgpD in the purple sulfur bacterium Allochromatium vinosum. Microorganisms 2023. doi: 10.3390/microorganisms11071792
Pan S, Jensen AA, Wood NA, Henrichfreise B, Brötz-Oesterhelt H, Fisher DJ, Sass P, Ouellette SP. Molecular characterization of the ClpC AAA+ ATPase in the biology of Chlamydia trachomatis. mBio 2023. doi: 10.1128/mbio.00075-23
Puls JS, Brajtenbach D, Schneider T, Kubitscheck U, Grein F. Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division. Sci Adv 2023. doi: 10.1126/sciadv.ade9023
Reuter J, Otten C, Jacquier N, Lee J, Mengin-Lecreulx D, Löckener I, Kluj R, Mayer C, Corona F, Dannenberg J, Aeby S, Bühl H, Greub G, Vollmer W, Ouellette SP, Schneider T, Henrichfreise B. An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis. Plos Pathogens 2023. doi: 10.1371/journal.ppat.1011047
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. A new antibiotic from an uncultured bacterium binds to an immutable target. Cell 2023. doi: 10.1016/j.cell.2023.07.038
Barbosa JC, Gonçalves S, Makowski M, Silva ÍC, Caetano T, Schneider T, Mösker E, Süssmuth RD, Santos NC, Mendo S. Insights into the mode of action of the two-peptide lantibiotic lichenicidin. Colloids Surf B Biointerfaces 2022.
Ersoy SC, Chan LC, Yeaman MR, Chambers HF, Proctor RA, Ludwig KC, Schneider T, Mann AC, Cheung A, Bayer AS. Impacts of NaHCO3 on ß-lactam binding to PBP2a protein variants associated with the NaHCO3-responsive versus NaHCO3-non-responsive phenotypes. Antibiotics 2022.
Kohga H, Mori T, Tanaka Y, Yoshidaie K, Taniguchi K, Fujimoto K, Fritz L, Schneider T, Tsukazaki T. Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms. Structure 2022.
Mendes SS, Marques J, Mesterhazy E, Straetener J, Arts M, Pissarro T, Reginold J, Berscheid A, Bornikoel J, Kluj RM, Mayer C, Oesterhelt F, Friaes S, Royo B, Schneider T, Brötz-Oesterhelt H, Romao CC, Saraiva LM. Synergetic antimicrobial activity and mechanism of Clotrimazole-linked CO-releasing molecules. ACS Bio Med Chem Au 2022.
Meringdal JW, Kilian A, Li WC, Heinemann MJB, Rausch M, Schneider T, Menche D. Modular synthesis of halogenated xanthones by a divergent coupling strategy. J Org Chem 2022.
Morris MA, Vallmitjana A, Grein F, Schneider T, Arts M, Jones CR, Nguyen BT, Hashemian MH, Malek M, Gratton E, Nowick JS. Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis. Chemical Science 2022.
Wingen LM, Braun C, Rausch M, Gross H, Schneider T, Menche D. Versatile synthesis of pathogen specific bacterial cell wall building blocks. RSC Adv 2022.
Drayton M, Deisinger JP, Ludwig KC, Raheem N, Müller A, Schneider T, Straus SK. Host defense peptides: dual antimicrobial and immunomodulatory action. Int J. Mol Sci.22(20):11172
Reithuber E, Wixe T, Ludwig KC, Müller A, Uvell H, Grein F, Lindgren AEG, Muschiol S, Nannapaneni P, Eriksson A, Schneider T, Normark S, Henriques-Normark B, Almqvist F, Mellroth P. THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates. Proc Natl Acad Sci.118(47):e2108244118
Wirtz DA, Ludwig KC, Arts M, Marx CE, Krannich S, Barac P, Kehraus S, Josten M, Henrichfreise B, Müller A, König GM, Peoples AJ, Nitti A, Spoering AL, Ling LL, Lewis K, Crüsemann M, Schneider T. Biosynthesis and mechanism of action of the cell wall targeting antibiotic hypeptin. Angew Chem Int. 60(24):13579-13586
Fernandes J.F., J. Held, M. Dorn, A. Lalremruata, F. Schaumburg, A. Alabi, M.D. Agbanrin, C. Kokou, A. Ben Adande, M. Esen, D. Eibach, A.A. Adegnika, S.T. Agnandji, B. Lell, I. Eckerle, B. Henrichfreise, B. Hogan, J. May, P.G. Kremsner, M.P. Grobusch, B. Mordmüller. Causes of fever in Gabonese children: a cross-sectional hospital-based study. Sci Rep.10:2080
Grein, F., A. Müller, K.M. Scherer, X. Liu, K.C. Ludwig, A. Klöckner, M. Strach, H.-G. Sahl, U. Kubitscheck, T. Schneider. Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids. Nat Commun. 11(1):1455
Ortiz-López F.J, D. Carretero-Molina, M. Sánchez-Hidalgo, J. Martín, I. González, F. Román-Hurtado, M. de la Cruz, S. García-Fernández, F. Reyes, J.P. Deisinger, A. Müller, T. Schneider, O. Genilloud. Cacaoidin, first member of the new lanthidin RiPP family. Angew Chem Int Ed Engl. 59(31):12654-12658
Wingen L.M., M. Rausch, T. Schneider, D. Menche. Modular total synthesis of farnesyl analogues of cell wall precursors lipid I and II containing the Staphylococcus aureus pentaglycine bridge modification. J Org Chem. 85(15):10206-10215
Wingen L.M., M. Rausch, T. Schneider, D. Menche. Synthesis of tetramic acid fragments derived from Vancoresmycin showing inhibitory effects towards S. aureus. Chem Med Chem. 15(15):1390-1393
Grein, F., T. Schneider, H.-G. Sahl. Docking on lipid II-A widespread mechanism for potent bactericidal activities of antibiotic peptides. J Mol Biol. 431(18):3520-3530
Jahanshah, G., Q. Yan, H. Gerhardt, Z. Pataj, M. Lämmerhofer, I. Pianet, M. Josten, H.-G. Sahl, M.W. Silby, J.E. Loper, H. Gross. Discovery of the cyclic lipopeptide gacamide A by genome mining and repair of the defective GacA regulator in Pseudomonas fluorescens Pf0-1. J Nat Prod. 82(2):301-308
Kaur, P., M. Rausch, B. Malakar, U. Watson, N.P. Damle, Y. Chawla, S. Srinivasan, K. Sharma, T. Schneider, G.D. Jhingan, D. Saini, D. Mohanty, F. Grein, V.K. Nandicoori. LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation. Nat Commun. 10(1):1231
Loeper, N.,S. Graspeuntner, S. Ledig, I. Kaufhold, F. Hoellen, A. Schiefer, B. Henrichfreise, K. Pfarr, A. Hoerauf, K. Shima, J. Rupp. Elaborations on corallopyronin A as a novel treatment strategy against genital chlamydial infections. Front. Microbiol. 10:943
Monteiro, J.M., G. Covas, D. Rausch, S.R. Filipe, T. Schneider, H.-G. Sahl, M.G. Pinho. The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity. Sci Rep. 9(1):5010. doi: 10.1038/s41598-019-41461-1
Pan, S., I.T. Malik, D. Thomy, B. Henrichfreise, P. Sass. The functional ClpXP protease of Chlamydia trachomatis requires distinct clpP genes from separate genetic loci. Sci Rep. 9(1):14129
Rausch, M., J.P. Deisinger, H. Ulm, A. Müller, W. Li, P. Hardt, X. Wang, X. Li, M. Sylvester, M. Engeser, W. Vollmer, C.E. Müller, H.-G. Sahl, J.C. Lee, T. Schneider. Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus. Nat Commun. 10(1):1404
Tan, S., K.C. Ludwig, A. Müller, T. Schneider, J.R. Nodwell. The lasso peptide siamycin-I targets lipid II at the gram-positive cell surface. ACS Chem Biol. 14(5):966-974
Bühl, H., D. Eibach, M. Nagel, G. Greub, N. Borel, N. Sarpong, T. Rettig, T. Pesch, S Aeby, A Klöckner, M Brunke, S Krannich, B Kreuels, E Owusu-Dabo, B Hogan, J May, B. Henrichfreise. Chlamydiae in febrile children with respiratory tract symptoms and age-matched controls, Ghana. New Microbes New Infect.22 :44-48
Harms, H., A. Klöckner, J. Schrör, M. Josten, S. Kehraus, M. Crüsemann, W. Hanke, T. Schneider, T.F. Schäberle, G.M. König. Antimicrobial dialkylresorcins from marine-derived microorganisms: insights into their mode of action an putative ecological relevance. Planta Med. 84(18):1363-1371
Hogan, B., D. Eibach, R. Krumkamp, N. Sarpong, D. Dekker, B. Kreuels, O. Maiga-Ascofaré, K. Gyau Boahen, C. Wiafe Akenten, Y. Adu-Sarkodie, E. Owusu-Dabo, J May; Fever Without Source (FWS) Study Group*. Malaria coinfections in febrile pediatric impatients: A hospital-based study from Ghana.*H. Bühl and B. Henrichfreise contributed as members of the FWS study group. Clin Infect Dis. 66(12):1838-1845
Lund, V.A., K. Wacnik, R.D. Turner, B.E. Cotterell, C.G. Walther, S.J. Fenn, F. Grein, S.J. Wollman, M.C. Leake, N. Olivier, A. Cadby, S. Mesnage, S. Jones, S.J. Foster. Molecular coordination of Staphylococcus aureus cell division.Elife. pii: e32057. doi: 10.7554/eLife.32057.
Müller, A., F. Grein, A. Otto, K. Gries, D. Orlov, V. Zarubaev, M. Girard, X. Sher, O. Shamova, T. Roemer, P. François, D. Becher, T. Schneider, H.-G. Sahl. Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.Int J Med Microbiol. 308(3):335-348
Segev-Zarko, L.A. G. Kapach, M. Josten, Y.A. Klug, H.G. Sahl, Y. Shai. 2018. Deficient lipid A remodeling by the arnB gene promotes biofilm formation in antimicrobial peptide susceptible Pseudomona aeruginosa. Biochemistry. 57(13):2024-2034
Weikum, J., N. Ritzmann, N. Jelden, A. Klöckner, S. Herkersdorf, M. Josten, H.-G. Sahl, F. Grein. Sulfide protects Staphylococcus aureus from aminoglycoside antibiotics but cannot be regarded as a general mechanism against antibiotics. Antimicrob Agents Chemother. 62(10)
Böhringer, N., K.M. Fisch, D. Schillo, R. Bara, C. Hertzer, F. Grein, J.H. Eisenbarth, F. Kaligis, T. Schneider, H. Wägele, G.M. König, T.F. Schäberle. Antimicrobial potential of bacteria associated with marine sea slugs from north Sulawesi, Indonesia. Front Microbiol. 8:1092
Eibach, D., M. Nagel, B. Hogan, C. Azuure, R. Krumkamp, D. Dekker, M. Gajdiss, M. Brunke, N. Sarpong, E. Owusu-Dabo. Nasal carriage of Staphylococcus aureus among children in the Ashanti region of Ghana. PLoS One. 12(1):e0170320
Hardt, P., I. Engels, M. Rausch, M. Gajdiss, H. Ulm, P. Sass, K. Ohlsen, H.-G. Sahl, G. Bierbaum, T. Schneider, F. Grein. 2017. The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus. J Med Microbiol. 307(1):1-10
Hufendiek, P., S.S.M. Stölben, S. Kehraus, N. Merten, H. Harms, M. Crüsemann, I. Arslan, M. Gütschow, T. Schneider, G.M. König. Biosynthetic studies on Acetosellin and structure elucidation of a new acetosellin derivative. Planta Med. 83(12-13):1044-1052
Müller, A. , A. Klöckner, T. Schneider. Targeting a cell wall biosynthesis hot spot. Nat Prod Rep. 34(7):909-932
Nair, D.R., J. Chen, J.M.Monteiro, M. Josten, M.G. Pinho, H.-G. Sahl, J. Wu, A. Cheung. A quinolinol-based small molecule with anti-MRSA activity that targets bacterial membrane and promotes fermentative metabolism. J Antibiot (Tokyo). 70(10):1009-1019
Schuster, D., J. Rickmeyer, M. Gajdiss, T. Thye, S. Lorenzen, M. Reif, M. Josten, C. Szekat, L.D.R. Melo, R.M. Schmithausen, Fl. Liégeois, H.-G. Sahl, J.-P. J. Gonzalez, M. Nagel, G. Bierbaum. Differentiation of Staphylococcus argenteus (formerly: Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape. Int J Med Microbiol. 307(1):57-63
Wilmes, M., K. Meier, A. Schiefer, M. Josten, C.F. Otten, A. Klöckner, B. Henrichfreise, W. Vollmer, A. Hörauf, K. Pfarr. AmiD is a novel peptidoglycan amidase in Wolbachia endosymbionts of Drosophila melanogaster. Front Cell Infect Microbiol. 7:353
Barac, P., H. Harms, I. Engels, S. Kehraus, T. Schneider, G.M. König. Fighting antibiotic resistance: resensitizing agents from marine derived fungi. Planta Med. 81(S01):S1-S381
Elnakady, A.Y., I. Chatterjee, M. Bischoff, M. Rohde, M. Josten, H.-G. Sahl, M. Herrmann, R. Müller. Investigations to the antibacterial mechanism of action of Kendomycin. PLoS One 11(1):e0146165
de Gier, M.G., H.B. Albada, M. Josten, R. Willems, H. Leavis, R. van Mansveld, F. L. Paganelli, B. Dekker, J.-W.J. Lammers, H.-G. Sahl, N. Metzler-Nolte. Synergistic activity of a short lipidated antimicrobial peptide (lipoAMP) and colistin or tobramycin against Pseudomonas aeruginosa from cystic fibrosis patients. MedChem Comm. 7:148-156
Henrich, E., Y. Ma, I. Engels, D. Münch, C. Otten, T. Schneider, B. Henrichfreise, H.-G. Sahl, V. Dötsch, F. Bernhard. Lipid requirements for the enzymatic activity of MraY translocases and in vitro reconstitution of lipid II synthesis pathway. J Biol Chem. 291(5):2535-46
Henrichfreise, B., M. Brunke, P. Viollier. Bacterial surfaces: The wall that SEDS built. Curr Biol. 26:R1158-R1160
Homma, T, A. Nuxoll, A.B. Gandt, P. Ebner, I. Engels, T. Schneider, F. Götz, K. Lewis, B.P. Conlon. Dual targeting of cell wall precursors by teixobactin leads to cell lysis. Antimicrob Agents Chemother. 60(11):6510-6517
Klöckner, A., H. Bühl, P. Viollier, B. Henrichfreise. Deconstructing the chlamydial cell wall. Curr Top Microbiol Immunol. 412:1-33
Klöckner A, M. Nagel, G. Greub, A. Sébastien, K. Hoffmann, F. Liegeois, F. Rouet, S. De Benedetti, N. Borel, B. Henrichfreise. Evidence for chlamydiae in free-living and captive great apes from central Africa. Emerg Infect Dis. 22:2199-2201.
Mann, P.A., A. Müller, K.A. Wolff, T. Fischmann, H. Wang, P. Reed, Y. Hou, W. Li, C.E. Müller, J. Xiao, N. Murgolo, X. Sher, T. Mayhood, P.R. Sheth, A. Mirza, M. Labroli, L. Xiao, M. McCoy, C.J. Gill, M.G. Pinho, T. Schneider, T. Roemer. Chemical genetic analysis and functional characterization of staphylococcal wall teichoic acid 2-epimerases reveals unconventional antibiotic drug targets. PLoS Pathog. 12(5):e1005585
Müller, A., M. Wenzel, H. Strahl, F. Grein, T.N. Saaki, B. Kohl, T. Siersma, J.E. Bandow, H.-G. Sahl, T. Schneider, L.W. Hamoen. Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains.precursors. PNAS.113(45):E7077-E7086
Ulm, H., T. Schneider. Targeting bactoprenol-coupled cell envelope precursors. Appl Microbiol Biotechnol. 100(18):7815-25
Scherer, K.M., J.H. Spille, H.-G. Sahl, F. Grein, U. Kubitscheck. The lantibiotic nisin induces lipid II aggregation, causing membrane instability and vesicle budding. Biophys J. 108(5):1114-24
Ling, L.L., T. Schneider, A.J. Peoples, A. L. Spoering, I. Engels, B.P. Conlon, A. Mueller, T.F. Schäberle, D.E. Hughes, S. Epstein, M. Jones, L. Lazarides, V.A. Steadman, D.R. Cohen, C.R. Felix, K.A. Fetterman, W.P. Millett, A.G. Nitti, A.M. Zullo, C. Chen, K.Lewis. A new antibiotic kills pathogens without detectable resistance. Nature. 517(7535):455-9
Münch, A., I. Engels, A. Müller, K. Reder-Christ, H. Falkenstein-Paul, G. Bierbaum, F. Grein, G. Bendas, H.-G. Sahl, T. Schneider. Structural variations of the cell wall precursor lipid II - Influence on binding and activity of the lipoglycopeptide antibiotic oritavancin. Antimicrob Agents Chemother. 59(2):772-81
Otten, C., S. De Benedetti, A. Gaballah, H. Bühl, A. Klöckner, J. Brauner, H.-G. Sahl, B. Henrichfreise. Co-solvents as stabilizing agents during heterologous overexpression in Escherichia coli – application to chlamydial penicillin-binding protein 6. PLoS One. 10(4):e0122110