De Benedetti S, Kirilov NK, Zeng H, Ade C, Bodenstein I, Förster M, Abdel-Wadood N, Aljohmani A, Krasteva-Christ G, Yildiz D, Junker S, Khalid SJ, Rox K, Schrey H, Grofle M, Schiefer A, Becker SL, Pfarr K, Hoerauf A, Bischoff M, Müsken M, Schneider T. Breaking down barriers: CorA effectively targets staphylococcal biofilms in vitro and in vivo. ChemMedChem. doi: 10.1002/cmdc.202501057

Karačić J, Grosse M, Pfarr K, Schiefer A, Schneider T, Hoerauf A, Karačić S, Parčina M, Hischebeth G, Fröschen FS, Bierbaum G. Corallopyronin A exhibits potent activity against staphylococci including MRSA and isolates from prosthetic infections. Infection. doi: 10.1007/s15010-026-02760-8. 

Klümpen L, Mantri A, Philipps M, Seel W, Schlautmann L, Yaghmour MH, Wiemann V, Stoffel-Wagner B, Coenen M, Weinhold L, Hasenauer J, Fließwasser T, Burgdorf S, Thiele C, Stehle P,  Simon M-C. Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial. Nat Commun. doi: 10.1038/s41467-026-68303-9

Kränkel L, Hauser J, Slavetinsky J, Zinser A, Schmidt A, Nega M, Elsherbini AMA, Schneider T, Gille C, Schaller M, Fuchs J, Peschel A, Slavetinsky C. Polygenic, cell-envelope adaptations drive high-frequency daptomycin resistance in Staphylococcus capitis NRCS-A from neonatal sepsis and NEC.  Antimicrob Agents Chemother. doi: 10.1128/aac.01414-25

Overman G, Loeckener I, Williford Z, Davis S, Diallo A, Blair J, Henrichfreise B, Liechti GW. Chlamydia trachomatis restricts signaling through NOD2 until late in the pathogen’s developmental cycle. Infect Immun. doi: 10.1128/iai.00472-25

Torres-Puschel D, Zimmer L, Kehraus S, Abdelrahman AA , Schneider T, Müller A, Carlier A, Crusemann, M. Paenidepsins are a family of lipopeptides from paenibacillus. J Nat Prod. doi: 10.1021/acs.jnatprod.5c01579

Deschner F, Mostert D, Daniel JM, Voltz A, Schneider DC, Khangholi N, Bartel J, de Carvalho LP, Brauer M, Gorelik TE, Kleeberg C, Risch T, Haeckl FPJ, Herraiz Benítez L, Andreas A, Kany AM, Jézéquel G, Hofer W, Müsken M, Held J, Bischoff M, Seemann R, Brötz-Oesterhelt H, Schneider T, Sieber S, Müller R, Herrmann J. Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets. Cell Chem Bio. doi: 10.1016/j.chembiol.2025.03.005

Rasheed S, Umstaetter F, Muehlberg E, Beijer B, Hertlein T, Klika KD, Kleist C, Werner J, Domhan C, Bingel M, Mueller A, Rausch M, Zimmermann S, Ohlsen K, Haberkorn U, Koch M, Bischoff M, Schneider T, Mueller R, Herrmann J, Mier W, Uhl P. Antibiotic-polycationic peptide conjugation as an effective strategy to overcome daptomycin resistance. Adv Therap. doi: 10.1002/adtp.202400473

Sugrue I, Ade C, O'Connor PM, Daniel JM, Innocenti P, Kirsch N, Martin NI, Weindl G, Hill C, Schneider T, Paul Ross R. Trans-kingdom conservation of mechanism between bacterial actifensin and eukaryotic defensins. NPJ Antimicrob Resist. doi: 10.1038/s44259-025-00135-x

Treiber T, Li WS , Bingel M, Müller A, Eckhardt M, Menche D. Total synthesis of epicoccolides A and B by oxidative skeleton rearrangement Leads to a structural revision and questions the proposed biosynthesis. Org Lett. doi: 10.1021/acs.orglett.5c02032

Adeniyi ET, Kruppa M, De Benedetti S, Ludwig KC, Krisilia V, Wassenberg TR, Both M, Schneider T, Müller TJJ, Kalscheuer R . Synthesis of bisindole alkaloids and their mode of action against methicillin-resistant Staphylococcus aureus. ACS Infect Dis. doi: 10.1021/acsinfecdis.3c00657  

Buijs NP, Vlaming HC, Kotsogianni I, Arts M, Willemse J, Duan Y, Alexander FM, Cochrane SA, Schneider T, Martin NI. A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2315310121

Dreckmann TM, Fritz L, Kaiser CF, Bouhired SM, Wirtz DA, Rausch M, Müller A, Schneider T, König GM, Crüsemann M. Biosynthesis of the corallorazines, a widespread class of antibiotic cyclic lipodipeptides. RSC Chem Biol. doi: 10.1039/d4cb00157e

Lewis K, Lee RE, Brötz-Oesterhelt H, Hiller S, Rodnina MV, Schneider T, Weingarth M, Wohlgemuth I. Sophisticated natural products as antibiotics.  Nature. doi: 10.1038/s41586-024-07530-w

Löckener I, Behrmann LV, Reuter J, Schiefer A, Klöckner A, Krannich S, Otten C, Mölleken K, Ichikawa S, Hoerauf A, Schneider T, Pfarr KM, Henrichfreise B. The MraY inhibitor muraymycin D2 and its derivatives induce enlarged cells in obligate intracellular Chlamydia and Wolbachia and break the persistence phenotype in Chlamydia. Antibiotics. doi: 10.3390/antibiotics13050421

Ludwig KC, Puls J-S, Matos de Opitz CL, Innocenti P, Daniel JM, Bornikoel J, Arts M, Krannich S, Straetener J, Brajtenbach D, Henrichfreise B, Sass P, Müller A, Martin NI, Brötz-Oesterhelt  H, Kubitscheck U, Grein F, Schneider T. The dual mode of antibacterial action of the synthetic small molecule DCAP involves lipid II binding.  JACS. doi: 10.1021/jacs.4c05138

van Groesen E, Mons E, Kotsogianni I, Arts M, Tehrani KHME, Wade N, Lysenko V, Stel FM, Zwerus JT, De Benedetti S, Bakker A, Chakraborty P, van der Stelt M, Scheffers DJ, Gooskens J, Smits WK, Holden K, Gilmour PS, Willemse J, Hitchcock CA, van Hasselt JGC, Schneider T, Martin NI. Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Sci Transl Med. doi: 10.1126/scitranslmed.abo4736 

Puls J-S, Winnerling B, Power JJ, Krüger AM, Brajtenbach D, Johnson M, Bilici K, Camus L, Fließwasser T, Schneider T, Sahl HG, Ghosal D, Kubitschek U, Heilbronner S, Grein F. Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action. ISME J. doi: 10.1093/ismejo/wrae044  

Voitsekhovskaia I, Ho YTC, Klatt C, Müller A, Machell DL, Tan YJ, Triesman M, Bingel M, Schittenhelm RB, Tailhades J, Kulik A, Maier ME, Otting G, Wohlleben W, Schneider T, Cryle M, Stegmann E. Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues. Proc Natl Acad Sci U S A. doi: 10.1039/d4cb00140k

Adolf LA, Müller-Jochim A, Kricks L, Puls JS, Lopez D, Grein F, Heilbronner S. Functional membrane microdomains and the hydroxamate siderophore transporter ATPase FhuC govern Isd-dependent heme acquisition in Staphylococcus aureus. Elife. doi:10.7554/eLife.85304.

Brajtenbach D, Puls JS, Matos de Opitz CL, Sass P, Kubitscheck U, Grein F. Quantitative analysis of microscopy data to evaluate bacterial responses to antibiotic treatment. Methods Mol Biol. doi: 10.1007/978-1-0716-2855-3_12

Deisinger JP, Arts M, Kotsogianni I, Puls JS, Grein F, Ortiz-Lopez FJ, Martin NI, Müller A, Genilloud O, Schneider T. Dual targeting of the class V lanthipeptide antibiotic cacaoidin. iScience. doi: 10.1016/j.isci.2023.106394

Kümpel C, Grein F, Dahl C. Fluorescence microscopy study of the intracellular sulfur globule protein SgpD in the purple sulfur bacterium Allochromatium vinosum. Microorganisms. doi: 10.3390/microorganisms11071792

Pan S, Jensen AA, Wood NA, Henrichfreise B, Brötz-Oesterhelt H, Fisher DJ, Sass P, Ouellette SP. Molecular characterization of the ClpC AAA+ ATPase in the biology of Chlamydia trachomatis. mBio. doi: 10.1128/mbio.00075-23

Puls JS, Brajtenbach D, Schneider T, Kubitscheck U, Grein F. Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division. Sci Adv. doi: 10.1126/sciadv.ade9023

Reuter J, Otten C, Jacquier N, Lee J, Mengin-Lecreulx D, Löckener I, Kluj R, Mayer C, Corona F, Dannenberg J, Aeby S, Bühl H, Greub G, Vollmer W, Ouellette SP, Schneider T, Henrichfreise B. An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis. Plos Pathogens. doi: 10.1371/journal.ppat.1011047

Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. A new antibiotic from an uncultured bacterium binds to an immutable target.  Cell. doi: 10.1016/j.cell.2023.07.038

Barbosa JC, Gonçalves S, Makowski M, Silva ÍC, Caetano T, Schneider T, Mösker E, Süssmuth RD, Santos NC, Mendo S. Insights into the mode of action of the two-peptide lantibiotic lichenicidin. Colloids Surf B Biointerfaces. doi: 10.1016/j.colsurfb.2021.112308

Ersoy SC, Chan LC, Yeaman MR, Chambers HF, Proctor RA, Ludwig KC, Schneider T, Mann AC, Cheung A, Bayer AS. Impacts of NaHCO3 on ß-lactam binding to PBP2a protein variants associated with the NaHCO3-responsive versus NaHCO3-non-responsive phenotypes. Antibiotics. doi: 10.3390/antibiotics11040462

Kohga H, Mori T, Tanaka Y, Yoshidaie K, Taniguchi K, Fujimoto K, Fritz L, Schneider T, Tsukazaki T. Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms. Structure. doi: 10.1016/j.str.2022.05.008

Mendes SS, Marques J, Mesterhazy E, Straetener J, Arts M, Pissarro T, Reginold J, Berscheid A, Bornikoel J, Kluj RM, Mayer C, Oesterhelt F, Friaes S, Royo B, Schneider T, Brötz-Oesterhelt H, Romao CC, Saraiva LM. Synergetic antimicrobial activity and mechanism of Clotrimazole-linked CO-releasing molecules. ACS Bio Med Chem Au. doi: 10.1021/acsbiomedchemau.2c00007

Meringdal JW, Kilian A, Li WC, Heinemann MJB, Rausch M, Schneider T, Menche D. Modular synthesis of halogenated xanthones by a divergent coupling strategy. J Org Chem. doi: 10.1021/acs.joc.2c01157

Morris MA, Vallmitjana A, Grein F, Schneider T, Arts M, Jones CR, Nguyen BT, Hashemian MH, Malek M, Gratton E, Nowick JS. Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis. Chemical Science. doi: /10.1039/d2sc01388f

Wingen LM, Braun C, Rausch M, Gross H, Schneider T, Menche D. Versatile synthesis of pathogen specific bacterial cell wall building blocks. RSC Adv. doi: 10.1039/d2ra01915a

Drayton M, Deisinger JP, Ludwig KC, Raheem N, Müller A, Schneider T, Straus SK. Host defense peptides: dual antimicrobial and immunomodulatory action. Int J. Mol Sci. doi: 10.3390/ijms222011172

Reithuber E, Wixe T, Ludwig KC, Müller A, Uvell H, Grein F, Lindgren AEG, Muschiol S, Nannapaneni P, Eriksson A, Schneider T, Normark S, Henriques-Normark B, Almqvist F, Mellroth P. THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates. Proc Natl Acad Sci. doi: 10.1073/pnas.2108244118

Wirtz  DA, Ludwig KC, Arts M, Marx CE, Krannich S, Barac P, Kehraus S, Josten M, Henrichfreise B, Müller A, König GM, Peoples AJ, Nitti A, Spoering AL, Ling LL, Lewis K, Crüsemann M, Schneider T. Biosynthesis and mechanism of action of the cell wall targeting antibiotic hypeptin. Angew Chem Int. doi: 10.1002/anie.202102224

Fernandes JF, Held J, Dorn M, Lalremruata A, Schaumburg F, Alabi A, Agbanrin MD, Kokou C, Ben Adande A, Esen M, Eibach D, Adegnika AA, Agnandji ST, Lell B, Eckerle I, Henrichfreise B, Hogan B, May J, Kremsner PG, Grobusch MP, Mordmüller B. Causes of fever in Gabonese children: a cross-sectional hospital-based study. Sci Rep. doi: 10.1038/s41598-020-58204-2

Grein F, Müller A, Scherer KM, Liu X, Ludwig KC, Klöckner A, Strach M, Sahl HG, Kubitscheck U, Schneider T. Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids. Nat Commun. doi: 10.1038/s41467-020-15257-1

Ortiz-López FJ, Carretero-Molina D, Sánchez-Hidalgo M, Martín J, González I, Román-Hurtado F, de la Cruz M, García-Fernández S, Reyes F, Deisinger JP, Müller A, Schneider T, Genilloud O.. Cacaoidin, first member of the new lanthidin RiPP family. Angew Chem Int Ed Engl. doi: 10.1002/anie.202005187

Wingen LM, Rausch M, Schneider T, Menche D. Modular total synthesis of farnesyl analogues of cell wall precursors lipid I and II containing the Staphylococcus aureus pentaglycine bridge modification. J Org Chem. doi: 10.1021/acs.joc.0c01004

Wingen LM, Rausch M, Schneider T, Menche D. Synthesis of tetramic acid fragments derived from Vancoresmycin showing inhibitory effects towards S. aureus. Chem Med Chem. doi: 10.1002/cmdc.202000241

Grein F, Schneider T, Sahl HG. Docking on lipid II-A widespread mechanism for potent bactericidal activities of antibiotic peptides. J Mol Biol. doi: 10.1016/j.jmb.2019.05.014

Jahanshah G, Yan Q, Gerhardt H, Pataj Z, Lämmerhofer M, Pianet I, Josten M, Sahl HG, Silby MW, Loper JE, Gross H. Discovery of the cyclic lipopeptide gacamide A by genome mining and repair of the defective GacA regulator in Pseudomonas fluorescens Pf0-1. J Nat Prod. doi: 10.1021/acs.jnatprod.8b00747

Kaur P, Rausch M, Malakar B, Watson U, Damle NP, Chawla Y, Srinivasan S, Sharma K, Schneider T, Jhingan GD, Saini D, Mohanty D, Grein F, Nandicoori VK. LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation. Nat Commun. doi: 10.1038/s41467-019-09223-9

Loeper N, Graspeuntner S, Ledig S, Kaufhold I, Hoellen F, Schiefer A, Henrichfreise B, Pfarr K, Hoerauf A, Shima K, Rupp J. Elaborations on corallopyronin A as a novel treatment strategy against genital chlamydial infections. Front. Microbiol. doi: 10.3389/fmicb.2019.00943

Monteiro JM, Covas G, Rausch D, Filipe SR, Schneider T, Sahl HG, Pinho MG. The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity. Sci Rep. 9(1):5010. doi: 10.1038/s41598-019-41461-1

Pan S, Malik IT, Thomy D, Henrichfreise B, Sass P. The functional ClpXP protease of Chlamydia trachomatis requires distinct clpP genes from separate genetic loci. Sci Rep. doi: 10.1038/s41598-019-50505-5

Rausch M, Deisinger JP, Ulm H, Müller A, Li W, Hardt P, Wang X, Li X, Sylvester M, Engeser M, Vollmer W, Müller CE, Sahl HG, Lee JC, Schneider T. Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus. Nat Commun. doi: 10.1038/s41467-019-09356-x

Tan S, Ludwig KC, Müller A, Schneider T, Nodwell JR. The lasso peptide siamycin-I targets lipid II at the gram-positive cell surface. ACS Chem Biol. doi: 10.1021/acschembio.9b00157

Bühl H, Eibach D, Nagel M, Greub G, Borel N, Sarpong N, Rettig T, Pesch T, Aeby S, Klöckner A, Brunke M, Krannich S, Kreuels B, Owusu-Dabo E, Hogan B, May J, Henrichfreise B. Chlamydiae in febrile children with respiratory tract symptoms and age-matched controls, Ghana. New Microbes New Infect. doi: 10.1016/j.nmni.2017.12.008

Harms H, Klöckner A, Schrör J, Josten M, Kehraus S, Crüsemann M, Hanke W, Schneider T, Schäberle TF, König GM. Antimicrobial dialkylresorcins from marine-derived microorganisms: insights into their mode of action an putative ecological relevance. Planta Med. doi: 10.1055/a-0653-7451

Hogan B, Eibach D, Krumkamp R, Sarpong N, Dekker D, Kreuels B, Maiga-Ascofaré O, Gyau Boahen K, Wiafe Akenten C, Adu-Sarkodie Y, Owusu-Dabo E, May J; Fever Without Source (FWS) Study Group*. Malaria coinfections in febrile pediatric impatients: A hospital-based study from Ghana.*Bühl H and Henrichfreise B contributed as members of the FWS study group. Clin Infect Dis. doi: 10.1093/cid/cix1120

Lund VA, Wacnik K, Turner RD, Cotterell BE, Walther CG, Fenn SJ, Grein F, Wollman AJ, Leake MC, Olivier N, Cadby A, Mesnage S, Jones S, Foster SJ. Molecular coordination of Staphylococcus aureus cell division. Elife. doi: 10.7554/eLife.32057

Müller A, Grein F, Otto A, Gries K, Orlov D, Zarubaev V, Girard M, Sher X, Shamova O, Roemer T, François P, Becher D, Schneider T, Sahl HG. Differential daptomycin resistance development in Staphylococcus aureus strains with active and mutated gra regulatory systems.Int J Med Microbiol. doi: 10.1016/j.ijmm.2017.12.002

Segev-Zarko LA, Kapach G, Josten M, Klug YA, Sahl HG, Shai Y. Deficient lipid A remodeling by the arnB gene promotes biofilm formation in antimicrobial peptide susceptible Pseudomona aeruginosa. Biochemistry. doi: 10.1021/acs.biochem.8b00149

Weikum J, Ritzmann N, Jelden N, Klöckner A, Herkersdorf S, Josten M, Sahl HG, Grein F. Sulfide protects Staphylococcus aureus from aminoglycoside antibiotics but cannot be regarded as a general mechanism against antibiotics.  Antimicrob Agents Chemother. doi: 10.1128/aac.00602-18

Böhringer N, Fisch KM, Schillo D, Bara R, Hertzer C, Grein F, Eisenbarth JH, Kaligis F, Schneider T, Wägele H, König GM, Schäberle TF. Antimicrobial potential of bacteria associated with marine sea slugs from north Sulawesi, Indonesia. Front Microbiol. doi: 10.3389/fmicb.2017.01092

Eibach D, Nagel M, Hogan B, Azuure C, Krumkamp R, Dekker D, Gajdiss M, Brunke M, Sarpong N, Owusu-Dabo E, May J. Nasal carriage of Staphylococcus aureus among children in the Ashanti region of Ghana. PLoS One. doi: 10.1371/journal.pone.0170320

Hardt P, Engels I, Rausch M, Gajdiss M, Ulm H, Sass P, Ohlsen K, Sahl HG, Bierbaum G, Schneider T, Grein F. The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus.  J Med Microbiol. doi: 10.1016/j.ijmm.2016.12.001

Hufendiek P, Stölben SSM, Kehraus S, Merten N, Harms H, Crüsemann M, Arslan I, Gütschow M, Schneider T, König GM. Biosynthetic studies on Acetosellin and structure elucidation of a new acetosellin derivative. Planta Med. doi: 10.1055/s-0042-124493

Müller A, Klöckner A, Schneider T. Targeting a cell wall biosynthesis hot spot. Nat Prod Rep. doi: 10.1039/c7np00012j

Nair DR, Chen J, Monteiro JM, Josten M, Pinho MG, Sahl HG, Wu J, Cheung A. A quinolinol-based small molecule with anti-MRSA activity that targets bacterial membrane and promotes fermentative metabolism. J Antibiot (Tokyo). doi: 10.1038/ja.2017.79

Schuster D, Rickmeyer J, Gajdiss M, Thye T, Lorenzen S, Reif M, Josten M, Szekat C, Melo LDR, Schmithausen RM, Liégeois F, Sahl HG, Gonzalez JJ, Nagel M, Bierbaum G. Differentiation of Staphylococcus argenteus (formerly: Staphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape. Int J Med Microbiol. doi: 10.1016/j.ijmm.2016.11.003

Wilmes M, Meier K, Schiefer A, Josten M, Otten CF, Klöckner A, Henrichfreise B, Vollmer W, Hoerauf A, Pfarr K. AmiD is a novel peptidoglycan amidase in Wolbachia endosymbionts of Drosophila melanogaster. Front Cell Infect Microbiol. doi: 10.3389/fcimb.2017.00353

Barac P, Harms H, Engels I, Kehraus S, Schneider T, König GM. Fighting antibiotic resistance: resensitizing agents from marine derived fungi. Planta Med. doi: 10.1055/s-0036-1596649

Elnakady YA, Chatterjee I, Bischoff M, Rohde M, Josten M, Sahl HG, Herrmann M, Müller R. Investigations to the antibacterial mechanism of action of Kendomycin. PLoS One. doi: 10.1371/journal.pone.0146165

de Gier MG, Albada HB, Josten M, Willems R, Leavis H, van Mansveld R, Paganelli FL, Dekker B, Lammers JWJ, Sahl HG, Metzler-Nolte N. Synergistic activity of a short lipidated antimicrobial peptide (lipoAMP) and colistin or tobramycin against Pseudomonas aeruginosa from cystic fibrosis patients. MedChem Comm. doi: 10.1039/C5MD00373C

Henrich E, Ma Y, Engels I, Münch D, Otten C, Schneider T, Henrichfreise B, Sahl HG, Dötsch V, Bernhard F. Lipid requirements for the enzymatic activity of MraY translocases and in vitro reconstitution of lipid II synthesis pathway. J Biol Chem. doi: 10.1074/jbc.m115.664292

Henrichfreise B, Brunke M, Viollier P. Bacterial surfaces: The wall that SEDS built. Curr Biol. doi: 10.1016/j.cub.2016.09.028

Homma T, Nuxoll A, Gandt AB, Ebner P, Engels I, Schneider T, Götz F, Lewis K, Conlon BP. Dual targeting of cell wall precursors by teixobactin leads to cell lysis. Antimicrob Agents Chemother. doi: 10.1128/aac.01050-16

Klöckner A, Bühl H, Viollier P, Henrichfreise B. Deconstructing the chlamydial cell wall. Curr Top Microbiol Immunol. doi: 10.1007/82_2016_34

Klöckner A, Nagel M, Greub G, Aeby S, Hoffmann K, Liégeois F, Rouet F, De Benedetti S, Borel N, Henrichfreise B. Chlamydia-related bacteria in free-living and captive Great Apes, Gabon. Emerg Infect Dis. doi: 10.3201/eid2212.150893

Mann PA, Müller A, Wolff KA, Fischmann T, Wang H, Reed P, Hou Y, Li W, Müller CE, Xiao J, Murgolo N, Sher X, Mayhood T, Sheth PR, Mirza A, Labroli M, Xiao L, McCoy M, Gill CJ, Pinho MG, Schneider T, Roemer T. Chemical genetic analysis and functional characterization of staphylococcal wall teichoic acid 2-epimerases reveals unconventional antibiotic drug targets. PLoS Pathog. doi: 10.1371/journal.ppat.1005585

Müller A, Wenzel M, Strahl H, Grein F, Saaki TNV, Kohl B, Siersma T, Bandow JE, Sahl HG, Schneider T, Hamoen LW. Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains.precursors. PNAS. doi: 10.1073/pnas.1611173113

Ulm H, Schneider T. Targeting bactoprenol-coupled cell envelope precursors. Appl Microbiol Biotechnol. doi: 10.1007/s00253-016-7732-0

Scherer KM, Spille JH, Sahl HG, Grein F, Kubitscheck U. The lantibiotic nisin induces lipid II aggregation, causing membrane instability and vesicle budding. Biophys J. doi: 10.1016/j.bpj.2015.01.020

Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K. A new antibiotic kills pathogens without detectable resistance. Nature. doi: 10.1038/nature14098

Münch D, Engels I, Müller A, Reder-Christ K, Falkenstein-Paul H, Bierbaum G, Grein F, Bendas G, Sahl HG, Schneider T. Structural variations of the cell wall precursor lipid II - Influence on binding and activity of the lipoglycopeptide antibiotic oritavancin. Antimicrob Agents Chemother. doi: 10.1128/aac.02663-14

Otten C, De Benedetti S, Gaballah A, Bühl H, Klöckner A, Brauner J, Sahl HG, Henrichfreise B. Co-solvents as stabilizing agents during heterologous overexpression in Escherichia coli – application to chlamydial penicillin-binding protein 6. PLoS One. doi: 10.1371/journal.pone.0122110